TFAP2E Antibody (PACO60172)
- SKU:
- PACO60172
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
TFAP2E Antibody (PACO60172)
The TFAP2E Polyclonal Antibody (PAC060172) is a valuable tool for researchers studying TFAP2E, a transcription factor known to play a role in various cellular processes, including development and cancer progression. This antibody, produced in rabbits, demonstrates high specificity and sensitivity towards human samples, making it ideal for use in Western blot experiments.TFAP2E, also known as AP-2 epsilon, is involved in the regulation of gene expression and has been implicated in the development of multiple cancer types.
Its role in controlling cell growth, differentiation, and metastasis makes it a promising target for cancer research. By targeting TFAP2E, researchers can gain insights into the molecular mechanisms underlying cancer progression and potentially identify new therapeutic strategies.Overall, the TFAP2E Polyclonal Antibody is a reliable tool for investigating the function and regulation of TFAP2E in various biological contexts, ultimately contributing to advancements in cancer research and drug development.
| Antibody Name: | TFAP2E Antibody (PACO60172) |
| Antibody SKU: | PACO60172 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:5000 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Transcription factor AP-2-epsilon protein (66-175AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western Blot. Positive WB detected in: MCF-7 whole cell lysate. All lanes: TFAP2E antibody at 3.63µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 47 kDa. Observed band size: 47 kDa. |
| Background: | Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP α and MYC. AP-2-epsilon may play a role in the development of the CNS and in cartilage differentiation (By similarity). |
| Synonyms: | Transcription factor AP-2-epsilon (AP2-epsilon) (Activating enhancer-binding protein 2-epsilon), TFAP2E |
| UniProt Protein Function: | AP-2 epsilon: Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2-epsilon may play a role in the development of the CNS and in cartilage differentiation. Belongs to the AP-2 family.Protein type: DNA-binding; Transcription factorChromosomal Location of Human Ortholog: 1p34.3Cellular Component: nucleusMolecular Function: protein homodimerization activity; protein heterodimerization activityBiological Process: transcription from RNA polymerase II promoter; regulation of transcription from RNA polymerase II promoter; anatomical structure development; positive regulation of transcription from RNA polymerase II promoter; regulation of cell proliferation |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q6VUC0 |
| NCBI GenInfo Identifier: | 194353976 |
| NCBI Gene ID: | 339488 |
| NCBI Accession: | NP_848643.2 |
| UniProt Secondary Accession: | Q6VUC0,Q8IW12 |
| UniProt Related Accession: | Q6VUC0 |
| Molecular Weight: | 46,212 Da |
| NCBI Full Name: | transcription factor AP-2-epsilon |
| NCBI Synonym Full Names: | transcription factor AP-2 epsilon (activating enhancer binding protein 2 epsilon) |
| NCBI Official Symbol: | TFAP2EÂ Â |
| NCBI Official Synonym Symbols: | AP2EÂ Â |
| NCBI Protein Information: | transcription factor AP-2-epsilon; AP2-epsilon; activating enhancer-binding protein 2-epsilon; adaptor-related protein complex 2, epsilon subunit |
| UniProt Protein Name: | Transcription factor AP-2-epsilon |
| UniProt Synonym Protein Names: | Activating enhancer-binding protein 2-epsilon |
| Protein Family: | Transcription factor |
| UniProt Gene Name: | TFAP2EÂ Â |
| UniProt Entry Name: | AP2E_HUMAN |
Related Products
TFAP2A/TFAP2B Antibody (PACO00401)
€319
TFAP2C Rabbit Polyclonal Antibody (CAB7739)
€139 - €419
TFAP2B Rabbit Polyclonal Antibody (CAB7935)
€139 - €419
Activator protein 2 (AP-2/TFAP2A) Polyclonal Antibody (CAB21727)
€129 - €359
Activator protein 2 (AP-2/TFAP2A) Rabbit Monoclonal Antibody (CAB2294)
€139 - €419
Activator protein 2 (AP-2/TFAP2A) Rabbit Polyclonal Antibody (CAB0416)
€139 - €419
Mouse Transcription factor AP-2-beta (Tfap2b) ELISA Kit (MOEB0411)
€649
Human Transcription factor AP-2-beta (TFAP2B) ELISA Kit (HUEB0699)
€649
Human TFAP2A/AP-2 ELISA Kit (HUFI06136)
€599