The TFAP2B Polyclonal Antibody (CAB7935) is a valuable tool for research involving TFAP2B, a transcription factor known for its role in development and disease. This antibody, produced in rabbits, is highly specific to human samples and is validated for use in Western blot applications. It targets the TFAP2B protein, allowing for detection and analysis in a variety of cell types, making it an ideal choice for studies in molecular biology and genetic research.TFAP2B, also known as transcription factor AP-2 beta, plays a crucial role in gene regulation and cellular differentiation, making it a key player in processes such as embryonic development and tissue homeostasis.
Dysregulation of TFAP2B has been linked to various diseases, including cancers and developmental disorders, highlighting its importance as a potential therapeutic target. By studying the function of TFAP2B, researchers can gain valuable insights into the mechanisms underlying these conditions and potentially identify new treatment strategies.Overall, the TFAP2B Polyclonal Antibody (CAB7935) is a valuable resource for researchers investigating the role of TFAP2B in health and disease. Its high specificity and reliability make it a trusted tool for exploring the complex functions of this transcription factor and its implications for human health.
Product Name:
TFAP2B Rabbit Polyclonal Antibody
SKU:
CAB7935
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human TFAP2B (Q92481).
This gene encodes a member of the AP-2 family of transcription factors. AP-2 proteins form homo- or hetero-dimers with other AP-2 family members and bind specific DNA sequences. They are thought to stimulate cell proliferation and suppress terminal differentiation of specific cell types during embryonic development. Specific AP-2 family members differ in their expression patterns and binding affinity for different promoters. This protein functions as both a transcriptional activator and repressor. Mutations in this gene result in autosomal dominant Char syndrome, suggesting that this gene functions in the differentiation of neural crest cell derivatives.
Purification Method:
Affinity purification
Gene ID:
7021
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates, using TFAP2B antibody (CAB7935) at 1:900 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
