Tf Antibody (PACO25536)
- SKU:
- PACO25536
- Product Type:
- Antibody
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
Tf Antibody (PACO25536)
The TF Polyclonal Antibody (PACO25536) is a versatile tool designed for research involving TF (Tissue Factor), a transmembrane glycoprotein that plays a crucial role in blood coagulation and inflammation. This antibody, produced in rabbits, is highly specific for human TF samples and has been validated for use in various applications, including Western blot and immunohistochemistry.TF is a key player in the coagulation cascade and is known for its role in initiating blood clot formation. Additionally, it has been implicated in inflammation and thrombosis, making it a target of interest in research related to cardiovascular disease, sepsis, and cancer.
By binding to TF, this antibody allows for the detection and analysis of TF expression in different cell types and tissues, providing valuable insights for studies in hemostasis, thrombosis, and inflammation.Understanding the function and regulation of TF is essential for developing therapeutic strategies to target coagulation disorders and inflammatory conditions. The TF Polyclonal Antibody (PACO25536) offers researchers a reliable tool to further investigate the role of TF in these processes, contributing to advancements in the fields of cardiovascular medicine, hematology, and oncology.
| Antibody Name: | Tf Antibody (PACO25536) |
| Antibody SKU: | PACO25536 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000 |
| Species Reactivity: | Rat |
| Immunogen: | Rat Transferrin (Native Protein) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot All lanes: Rat Transferrin antibody at 2µg/ml Lane 1: Rat Transferrin at 0.2 mg Lane 2: Rat Transferrin at 0.1 mg Secondary Goat polyclonal to rabbit IgG at 1/15000 dilution Predicted band size: 77, 55 kDa Observed band size: 77 kDa . |
| Background: | Transferrin is a single polypeptide chain glycoprotein and is a member of the iron binding family of proteins. It has a molecular weight of 77 kDa and a serum concentration range of 1800 to 2700 mg/L. It is synthesized in the liver and consists of two domains each having a high affinity reversible binding site for Fe3+. Iron is transported in blood and interstitial fluids to sites of use and disposal. Iron/transferrin is essential in hemoglobin synthesis and for certain types of cell division. Serum concentration rises in iron deficiency and pregnancy and falls in iron overload, infection and inflammatory conditions. |
| Synonyms: | Serotransferrin (Transferrin) (Beta-1 metal-binding globulin) (Liver regeneration-related protein LRRG03) (Siderophilin), Tf |
| UniProt Protein Function: | Transferrins are iron binding transport proteins which can bind two Fe3+ ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation. |
| NCBI Summary: | plays a role iin iron transport and homeostasis [RGD, Feb 2006] |
| UniProt Code: | P12346 |
| NCBI GenInfo Identifier: | 61556986 |
| NCBI Gene ID: | 24825 |
| NCBI Accession: | NP_001013128.1 |
| UniProt Secondary Accession: | P12346,Q63602, Q64628, Q64630, Q7TNX0, |
| UniProt Related Accession: | P12346 |
| Molecular Weight: | 76 |
| NCBI Full Name: | serotransferrin |
| NCBI Synonym Full Names: | transferrin |
| NCBI Official Symbol: | Tf  |
| NCBI Official Synonym Symbols: | Tfn; Trf  |
| NCBI Protein Information: | serotransferrin |
| UniProt Protein Name: | Serotransferrin |
| UniProt Synonym Protein Names: | Beta-1 metal-binding globulin; Liver regeneration-related protein LRRG03; Siderophilin |
| UniProt Gene Name: | Tf  |
| ELISA Kits |
| Rat Serotransferrin (Tf) ELISA Kit |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
Related Products
Tf Antibody (PACO63863)
Rat Tissue Factor (TF) ELISA Kit
Human Tissue Factor (TF) ELISA Kit
Human Serotransferrin (TF) ELISA Kit (HUEB2122)
Mouse Tissue Factor (TF) ELISA Kit
