The TET3 Polyclonal Antibody (CAB17310) is a powerful tool for researchers studying TET3, an enzyme involved in DNA demethylation and gene expression regulation. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards human samples, making it ideal for use in Western blot applications. By targeting the TET3 protein, researchers can easily detect and analyze its expression in a variety of cell types, aiding in studies related to epigenetics, cancer biology, and developmental biology.
TET3 plays a crucial role in DNA demethylation processes, which are essential for the proper regulation of gene expression and cell differentiation. Dysregulation of TET3 activity has been linked to various diseases, including cancer and neurological disorders, highlighting the importance of studying its function. By utilizing the TET3 Polyclonal Antibody, researchers can gain valuable insights into the role of TET3 in disease development and potentially identify novel therapeutic targets for intervention.
Product Name:
TET3 Rabbit Polyclonal Antibody
SKU:
CAB17310
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1551-1650 of human TET3 (NP_001274420.1).
Enables methyl-CpG binding activity and zinc ion binding activity. Involved in histone H3-K4 trimethylation; positive regulation of transcription by RNA polymerase II; and protein O-linked glycosylation. Predicted to be located in cytoplasm and male pronucleus. Predicted to be active in nucleus. Biomarker of esophagus squamous cell carcinoma.
Purification Method:
Affinity purification
Gene ID:
200424
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from mESCs cells, using TET3 Rabbit pAb (CAB17310) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
