The Tet1 Polyclonal Antibody (CAB1506) is a valuable tool for researchers studying Tet1, an enzyme involved in DNA demethylation and gene regulation. This antibody, raised in rabbits, is highly specific to Tet1 and has been validated for use in various applications, including Western blotting. By targeting the Tet1 protein, this antibody allows for the detection and analysis of Tet1 expression in different cell types, making it ideal for studies in epigenetics and cancer research.Tet1 is known for its role in DNA demethylation, which is crucial for regulating gene expression and cellular differentiation.
Dysregulation of Tet1 has been linked to various diseases, including cancer and neurodevelopmental disorders. Therefore, understanding the function and regulation of Tet1 is essential for developing targeted therapies and diagnostic tools for these conditions.Overall, the Tet1 Polyclonal Antibody (CAB1506) is a valuable tool for researchers investigating the role of Tet1 in epigenetic regulation and disease pathogenesis. Its high specificity and reliability make it a trusted reagent for experiments aiming to unravel the complex mechanisms underlying Tet1 function.
Product Name:
TET1 Rabbit Polyclonal Antibody
SKU:
CAB1506
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1800-1900 of human TET1 (NP_085128.2).
DNA methylation is an epigenetic mechanism that is important for controlling gene expression. The protein encoded by this gene is a demethylase that belongs to the TET (ten-eleven translocation) family. Members of the TET protein family play a role in the DNA methylation process and gene activation.
Purification Method:
Affinity purification
Gene ID:
80312
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates using TET1 Rabbit pAb (CAB1506) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 180s.
