The TESK2 Polyclonal Antibody (CAB13395) is a valuable tool for researchers studying TESK2, a protein kinase involved in actin cytoskeleton organization and cell migration. This antibody, raised in rabbits, has high specificity for human samples and is validated for use in Western blot applications. By binding to TESK2, the antibody enables detection and analysis in a variety of cell types, making it ideal for studies in cell biology and cancer research.TESK2 plays a crucial role in the regulation of actin dynamics, which is essential for various cellular processes such as cell shape maintenance, cell migration, and cell division.
Dysregulation of TESK2 has been linked to cancer progression and metastasis, making it a promising target for therapeutic intervention. Understanding the function of TESK2 is key to developing novel treatments for cancer and other diseases involving abnormal cell migration.Overall, the TESK2 Polyclonal Antibody is a reliable tool for researchers investigating the role of TESK2 in cellular processes and disease, with the potential to advance our understanding of cancer biology and identify new therapeutic targets.
Product Name:
TESK2 Rabbit Polyclonal Antibody
SKU:
CAB13395
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 302-571 of human TESK2 (NP_009101.2).
This gene product is a serine/threonine protein kinase that contains an N-terminal protein kinase domain that is structurally similar to the kinase domains of testis-specific protein kinase-1 and the LIM motif-containing protein kinases (LIMKs). Its overall structure is most related to the former, indicating that it belongs to the TESK subgroup of the LIMK/TESK family of protein kinases. This gene is predominantly expressed in testis and prostate. The developmental expression pattern of the rat gene in testis suggests an important role for this gene in meitoic stages and/or early stages of spermiogenesis. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
10420
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using TESK2 antibody (CAB13395) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 1s.
