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TESK1 Antibody (PACO22317)

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SKU:
PACO22317
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
WB
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
€419

Description

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TESK1 Antibody (PACO22317)

The TESK1 Polyclonal Antibody (PACO22317) is a powerful tool for researchers studying the TESK1 protein, an enzyme involved in cell signaling pathways and cytoskeletal organization. This antibody, produced in rabbits, exhibits high specificity and sensitivity for detecting TESK1 in human samples, making it an ideal choice for Western blot applications.TESK1 plays a pivotal role in regulating actin dynamics and cell migration, making it a key player in processes such as cell division, adhesion, and motility. Dysregulation of TESK1 has been linked to various diseases, including cancer and neurological disorders, highlighting its importance as a potential therapeutic target.

By utilizing the TESK1 Polyclonal Antibody, researchers can gain valuable insights into the function and regulation of TESK1 in different cell types and experimental settings. This antibody enables precise detection and analysis of TESK1 levels, offering a valuable tool for studies focused on cell biology, cancer research, and drug development.

Antibody Name:TESK1 Antibody (PACO22317)
Antibody SKU:PACO22317
Size:100ul
Host Species:Rabbit
Tested Applications:ELISA, WB
Recommended Dilutions:ELISA:1:2000-1:10000, WB:1:500-1:3000
Species Reactivity:Human
Immunogen:Synthesized peptide derived from internal of human TESK1.
Form:Liquid
Storage Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Product ImageWestern blot analysis of extracts from rat heart cells, rat kidney cells and rat liver cells, using TESK1 antibody.
Background:Dual specificity protein kinase activity catalyzing autophosphorylation and phosphorylation of exogenous substrates on both serine/threonine and tyrosine residues. Probably plays a central role at and after the meiotic phase of spermatogenesis By similarity.
Synonyms:EC 2.7.12.1; TES1; Testicular protein kinase 1; Testis-specific protein kinase 1;
UniProt Protein Function:TESK1: a TKL kinase of the LISK fanily. Its testicular germ cell-specific expression and developmental pattern of expression in the mouse suggests that this kinase plays an important role at and after the meiotic phase of spermatogenesis.Protein type: EC 2.7.12.1; Protein kinase, TKL; Kinase, protein; Protein kinase, Ser/Thr (non-receptor); TKL group; LISK family; TESK subfamilyChromosomal Location of Human Ortholog: 9p13Cellular Component: cytosolMolecular Function: protein binding
UniProt Protein Details:
NCBI Summary:This gene product is a serine/threonine protein kinase that contains an N-terminal protein kinase domain and a C-terminal proline-rich domain. Its protein kinase domain is most closely related to those of the LIM motif-containing protein kinases (LIMKs). The encoded protein can phosphorylate myelin basic protein and histone in vitro. The testicular germ cell-specific expression and developmental pattern of expression of the mouse gene suggests that this gene plays an important role at and after the meiotic phase of spermatogenesis. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015]
UniProt Code:Q15569
NCBI GenInfo Identifier:209572684
NCBI Gene ID:7016
NCBI Accession:Q15569.2
UniProt Secondary Accession:Q15569,Q8IXZ8
UniProt Related Accession:Q15569
Molecular Weight:67,684 Da
NCBI Full Name:Dual specificity testis-specific protein kinase 1
NCBI Synonym Full Names:testis-specific kinase 1
NCBI Official Symbol:TESK1  
NCBI Official Synonym Symbols:
NCBI Protein Information:dual specificity testis-specific protein kinase 1
UniProt Protein Name:Dual specificity testis-specific protein kinase 1
UniProt Synonym Protein Names:Testicular protein kinase 1
Protein Family:Dual specificity testis-specific protein kinase
UniProt Gene Name:TESK1  
UniProt Entry Name:TESK1_HUMAN
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