TES Rabbit Polyclonal Antibody (CAB7094)
- SKU:
- CAB7094
- Product Type:
- Antibody
- Reactivity:
- Human
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Product Name: | TES Rabbit Polyclonal Antibody |
SKU: | CAB7094 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human TES (NP_056456.1). |
Sequence: | MDLE NKVK KMGL GHEQ GFGA PCLK CKEK CEGF ELHF WRKI CRNC KCGQ EEHD VLLS NEED RKVG KLFE DTKY TTLI AKLK SDGI PMYK RNVM ILTN PVAA KKNV SINT VTYE WAPP VQNQ ALAR QYMQ MLPK EKQP VAGS EGAQ YRKK QLAK QLPA HDQD PSKC HELS PREV KEME QFVK KYKS EALG VGDV KLPC EMDA QGPK QMNI PGGD RSTP AAVG AMED KSAE HKRT QYSC YCCK LSMK EGDP AIYA ERAG YDKL |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 |
Synonyms: | TESS; TESS-2; TES |
Positive Sample: | HeLa,22Rv1,Rat ovary |
Conjugate: | Unconjugated |
Cellular Localization: | Cell junction, Cytoplasm, focal adhesion. |
Calculated MW: | 48kDa |
Observed MW: | 47kDa |
Cancer-associated chromosomal changes often involve regions containing fragile sites. This gene maps to a commom fragile site on chromosome 7q31.2 designated FRA7G. This gene is similar to mouse Testin, a testosterone-responsive gene encoding a Sertoli cell secretory protein containing three LIM domains. LIM domains are double zinc-finger motifs that mediate protein-protein interactions between transcription factors, cytoskeletal proteins and signaling proteins. This protein is a negative regulator of cell growth and may act as a tumor suppressor. This scaffold protein may also play a role in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton. Multiple protein isoforms are encoded by transcript variants of this gene.
Purification Method: | Affinity purification |
Gene ID: | 26136 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |