The TERF2IP Polyclonal Antibody (CAB7981) is specifically designed for research involving TERF2IP, a protein involved in telomere maintenance and DNA repair processes. This antibody, raised in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By binding to the TERF2IP protein, this antibody enables accurate detection and analysis in various cell types, making it ideal for studies in molecular biology and cancer research.TERF2IP, also known as telomeric repeat-binding factor 2-interacting protein, plays a crucial role in maintaining telomere integrity and chromosome stability.
Its involvement in DNA repair mechanisms makes it a valuable target for research into genetic diseases, cancer, and aging. Understanding the function of TERF2IP is essential for uncovering its potential therapeutic implications in these contexts.Overall, the TERF2IP Polyclonal Antibody (CAB7981) provides researchers with a powerful tool for investigating the role of TERF2IP in cellular processes, offering new insights into its biological functions and potential applications in disease research and therapy.
Product Name:
TERF2IP Rabbit Polyclonal Antibody
SKU:
CAB7981
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human TERF2IP (NP_061848.2).
Enables G-rich strand telomeric DNA binding activity and phosphatase binding activity. Involved in several processes, including positive regulation of NIK/NF-kappaB signaling; regulation of nucleobase-containing compound metabolic process; and regulation of protein modification process. Located in chromosome, telomeric region; cytosol; and nuclear body. Part of shelterin complex.
Purification Method:
Affinity purification
Gene ID:
54386
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using TERF2IP antibody (CAB7981) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
