The TENM1 Polyclonal Antibody (CAB15774) is a valuable tool for researchers studying TENM1, a member of the teneurin family of transmembrane proteins involved in cell adhesion and neuronal development. This antibody, raised in rabbits, demonstrates high reactivity with human samples and has been validated for use in Western blot applications. By binding to the TENM1 protein, this antibody enables researchers to detect and analyze its expression in various cell types, making it a versatile tool for studies in neuroscience, developmental biology, and neurodegenerative diseases.
TENM1 is known to play a crucial role in neuronal development, axon guidance, and synapse formation in the central nervous system. Its implication in cell adhesion processes and interactions with other proteins make it a key player in neural circuit formation and maintenance. Understanding the function and regulation of TENM1 is essential for unraveling the complexities of brain development and neuroplasticity, with potential implications for the treatment of neurological disorders and cognitive impairments.
Product Name:
TENM1 Rabbit Polyclonal Antibody
SKU:
CAB15774
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 350-540 of human TENM1 (NP_001156750.1).
The protein encoded by this gene belongs to the tenascin family and teneurin subfamily. It is expressed in the neurons and may function as a cellular signal transducer. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
10178
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using TENM1 Rabbit pAb (CAB15774) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.