The TEFM Polyclonal Antibody (CAB8511) is a valuable tool for researchers studying the TEFM protein, which plays a crucial role in mitochondrial transcription and replication processes. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications, enabling the detection and analysis of TEFM in various cell types.TEFM, also known as Transcription Elongation Factor M, is essential for the transcription of mitochondrial DNA and maintenance of mitochondrial function. Dysregulation of TEFM has been implicated in various diseases, including mitochondrial disorders and cancer.
Therefore, studying the function and expression of TEFM using this antibody can provide important insights into mitochondrial biology and disease pathology.With its specificity and sensitivity, the TEFM Polyclonal Antibody is an invaluable tool for researchers in the fields of molecular biology, genetics, and mitochondrial research. By enabling the accurate detection of TEFM protein levels, this antibody can aid in the development of targeted therapies for diseases associated with mitochondrial dysfunction.
Product Name:
TEFM Rabbit Polyclonal Antibody
SKU:
CAB8511
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 36-210 of human TEFM (NP_078959.3).
Enables DNA polymerase processivity factor activity. Involved in mitochondrial transcription and oxidative phosphorylation. Located in mitochondrial nucleoid. Part of ribonucleoprotein complex.
Purification Method:
Affinity purification
Gene ID:
79736
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of lysates from A549 cells, using TEFM Rabbit pAb (CAB8511) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 20s.
