The TEC Monoclonal Antibody is a valuable tool for researchers studying TEC, a tyrosine kinase involved in immune cell development and function. This antibody, produced through monoclonal antibody technology, has high specificity and sensitivity for TEC protein detection in various cell types and tissues. Validated for use in applications such as immunofluorescence and flow cytometry, the TEC Monoclonal Antibody enables precise analysis of TEC expression and localization within cells.
TEC is a key regulator of immune cell signaling and activation, making it a crucial target for understanding immune responses and developing targeted therapies. Dysregulation of TEC has been implicated in various immune-related diseases, including autoimmune disorders and leukemia. By utilizing the TEC Monoclonal Antibody in their studies, researchers can further investigate the role of TEC in these diseases and potentially identify new therapeutic approaches.
Product Name:
Tec Monoclonal Antibody
SKU:
CAB22074
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human Tec (NP_003206.2).
The protein encoded by this gene belongs to the Tec family of non-receptor protein-tyrosine kinases containing a pleckstrin homology domain. Tec family kinases are involved in the intracellular signaling mechanisms of cytokine receptors, lymphocyte surface antigens, heterotrimeric G-protein coupled receptors, and integrin molecules. They are also key players in the regulation of the immune functions. Tec kinase is an integral component of T cell signaling and has a distinct role in T cell activation. This gene may be associated with myelodysplastic syndrome.
Purification Method:
Affinity purification
Gene ID:
7006
Clone Number:
ARC53949
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of Rat liver, using Tec antibody (CAB22074) at 1:10000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
