The TEAD4 Polyclonal Antibody (CAB4151) is a valuable tool for researchers studying TEAD4, a transcription factor that plays a key role in regulating gene expression and cell proliferation. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. It binds specifically to the TEAD4 protein, allowing for accurate detection and analysis in a variety of cell types.TEAD4 is a critical player in various cellular processes, including development, stem cell pluripotency, and tumorigenesis. Its dysregulation has been implicated in a range of diseases, making it an attractive target for studies in cancer biology, regenerative medicine, and developmental biology.
By understanding the function of TEAD4, researchers can gain insights into the mechanisms underlying these diseases and potentially uncover new therapeutic strategies.Overall, the TEAD4 Polyclonal Antibody (CAB4151) is a valuable tool for researchers looking to explore the role of TEAD4 in different biological processes and disease contexts. Its high specificity and reliability make it a trusted partner in advancing scientific knowledge and potentially finding new treatment avenues.
Product Name:
TEAD4 Rabbit Polyclonal Antibody
SKU:
CAB4151
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 110-250 of human TEAD4 (NP_003204.2).
This gene product is a member of the transcriptional enhancer factor (TEF) family of transcription factors, which contain the TEA/ATTS DNA-binding domain. It is preferentially expressed in the skeletal muscle, and binds to the M-CAT regulatory element found in promoters of muscle-specific genes to direct their gene expression. Alternatively spliced transcripts encoding distinct isoforms, some of which are translated through the use of a non-AUG (UUG) initiation codon, have been described for this gene.
Purification Method:
Affinity purification
Gene ID:
7004
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using TEAD4 antibody (CAB4151) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
