The TEAD4 Monoclonal Antibody is a valuable tool for researchers studying TEAD4, a transcriptional factor involved in various cellular processes, including cell proliferation and differentiation. This antibody, produced using cutting-edge technology, specifically targets TEAD4 in human samples and is validated for use in immunofluorescence and immunohistochemistry applications.TEAD4, a key player in the Hippo signaling pathway, regulates gene expression and influences cell fate decisions.
Its role in controlling organ size and tumorigenesis makes it a compelling target for cancer research and regenerative medicine studies. The TEAD4 Monoclonal Antibody offers researchers a reliable means to detect and analyze TEAD4 expression in different cell types, aiding in the understanding of its functional mechanisms and potential therapeutic applications.
Product Name:
TEAD4 Monoclonal Antibody
SKU:
CAB23774
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 140-240 of human TEAD4 (Q15561).
Sequence:
SATA FHSS MALA RGPG RPAV SGFW QGAL PGQA GTSH DVKP FSQQ TYAV QPPL PLPG FESP AGPA PSPS APPA PPWQ GRSV ASSK LWML EFSA FLEQ QQDP D
This gene product is a member of the transcriptional enhancer factor (TEF) family of transcription factors, which contain the TEA/ATTS DNA-binding domain. It is preferentially expressed in the skeletal muscle, and binds to the M-CAT regulatory element found in promoters of muscle-specific genes to direct their gene expression. Alternatively spliced transcripts encoding distinct isoforms, some of which are translated through the use of a non-AUG (UUG) initiation codon, have been described for this gene.
Purification Method:
Affinity purification
Gene ID:
7004
Clone Number:
ARC59949
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates, using TEAD4 Rabbit mAb (CAB23774) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
