The TEAD1 Rabbit Monoclonal Antibody (CAB5218) is a cutting-edge tool for researchers studying TEAD1, a transcription factor that plays a key role in regulating gene expression and cell growth. This antibody, developed and validated for use in various research applications, specifically recognizes TEAD1 in human samples with high specificity and sensitivity.TEAD1 is a critical player in the Hippo signaling pathway, which controls organ size, tissue regeneration, and tumorigenesis. Dysregulation of TEAD1 has been linked to various diseases, including cancer and developmental disorders.
By targeting TEAD1 with this monoclonal antibody, researchers can gain valuable insights into its function and potential therapeutic applications.This TEAD1 antibody is suitable for use in techniques such as immunohistochemistry, immunofluorescence, and Western blotting, enabling detailed studies of TEAD1 expression, localization, and interactions in different cell types and tissues. Its high affinity and specificity make it an essential tool for advancing our understanding of TEAD1 biology and its impact on health and disease.
Product Name:
TEAD1 Rabbit Monoclonal Antibody
SKU:
CAB5218
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human TEAD1 (P28347).
This gene encodes a ubiquitous transcriptional enhancer factor that is a member of the TEA/ATTS domain family. This protein directs the transactivation of a wide variety of genes and, in placental cells, also acts as a transcriptional repressor. Mutations in this gene cause Sveinsson's chorioretinal atrophy. Additional transcript variants have been described but their full-length natures have not been experimentally verified.
Purification Method:
Affinity purification
Gene ID:
7003
Clone Number:
ARC1157
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
CUT&Tag was performed using the CUT&Tag Assay Kit (pAG-Tn5) for Illumina(RK20265) from 10⁵ Hep G2 cells with 1 μg TEAD1 Rabbit mAb (CAB5218), along with a Goat Anti-Rabbit IgG(H+L). The CUT&Tag results indicate the enrichment pattern of TEAD1 in representative gene loci (SLC7A5), as shown in figure.
