TDP-43/TARDB Rabbit Monoclonal Antibody (CAB19123)
- SKU:
- CAB19123
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | TDP-43/TARDB Rabbit Monoclonal Antibody |
SKU: | CAB19123 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 300-400 of human TDP-43/TARDB (Q13148). |
Sequence: | GNNQ GSNM GGGM NFGA FSIN PAMM AAAQ AALQ SSWG MMGM LASQ QNQS GPSG NNQN QGNM QREP NQAF GSGN NSYS GSNS GAAI GWGS ASNA GSGS GFNG G |
Tested Applications: | WB IHC-P IF/ICC IP ChIP ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 IP,0.5μg-4μg antibody for 400μg-600μg extracts of whole cellsChIP,5μg antibody for 10μg-15μg of Chromatin |
Synonyms: | ALS10; TDP-43; TDP-43/TARDBP |
Positive Sample: | HeLa, A549,K-562,Mouse brain,Mouse testis,Mouse thymus,Rat brain,Rat liver,K-562 |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 45kDa |
Observed MW: | 35kDa/45kDa/45kDa |
HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20.
Purification Method: | Affinity purification |
Gene ID: | 23435 |
Clone Number: | ARC0492 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |