TDO2 Rabbit Polyclonal Antibody (CAB13182)
- SKU:
- CAB13182
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | TDO2 Rabbit Polyclonal Antibody |
SKU: | CAB13182 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 100-200 of human TDO2 (NP_005642.1). |
Sequence: | VLQN MRVP YNRR HYRD NF |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IF/ICC,1:100 - 1:500 |
Synonyms: | TO; TDO; TPH2; TRPO; HYPTRP; TDO2 |
Positive Sample: | HT-29,Mouse liver |
Conjugate: | Unconjugated |
Cellular Localization: | cytosol |
Calculated MW: | 48kDa |
Observed MW: | 48kDa |
This gene encodes a heme enzyme that plays a critical role in tryptophan metabolism by catalyzing the first and rate-limiting step of the kynurenine pathway. Increased activity of the encoded protein and subsequent kynurenine production may also play a role in cancer through the suppression of antitumor immune responses, and single nucleotide polymorphisms in this gene may be associated with autism.
Purification Method: | Affinity purification |
Gene ID: | 6999 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |