The TDGF1 Polyclonal Antibody (CAB1065) is a valuable tool for researchers studying TDGF1, a pluripotent marker associated with embryonic stem cells and early development processes. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for Western blot applications. By specifically targeting the TDGF1 protein, researchers can accurately detect and analyze its expression in a variety of cell types, making it suitable for investigations in developmental biology, stem cell research, and cancer studies.
TDGF1, also known as Cripto-1, is a key regulator of embryonic development and plays a crucial role in cell differentiation and proliferation. Its involvement in pathways related to stem cell maintenance and early embryogenesis makes it a promising target for research on regenerative medicine, cancer biology, and developmental disorders. Understanding the functions of TDGF1 can provide insights into potential therapeutic strategies for various diseases and conditions linked to aberrant cell growth and differentiation.
Product Name:
TDGF1 Rabbit Polyclonal Antibody
SKU:
CAB1065
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 31-150 of human TDGF1 (NP_001167607.1).
This gene encodes an epidermal growth factor-related protein that contains a cripto, FRL-1, and cryptic domain. The encoded protein is an extracellular, membrane-bound signaling protein that plays an essential role in embryonic development and tumor growth. Mutations in this gene are associated with forebrain defects. Pseudogenes of this gene are found on chromosomes 2, 3, 6, 8, 19 and X. Alternate splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
6997
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of lysates from NCCIT cells, using TDGF1 Rabbit pAb (CAB1065) at 1:900 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
