The TCTEX1D2 Polyclonal Antibody (PAC039214) is a valuable tool for researchers studying TCTEX1D2, a protein involved in various cellular processes, including intracellular transport and cell division. This antibody, developed through immunization of rabbits, exhibits high specificity and sensitivity towards human samples, making it suitable for use in Western blot assays. By binding to the TCTEX1D2 protein, this antibody enables researchers to detect and analyze its presence in different cell types, making it particularly useful for investigations in cell biology and cancer research.
TCTEX1D2, also known as Tctex1 domain-containing protein 2, is a key player in cellular functions related to cytoskeleton organization and intracellular transportation. Its involvement in these processes points to its potential significance in cancer progression and other diseases related to aberrant cell division. By studying the role of TCTEX1D2 in cellular pathways, researchers can gain valuable insights into the mechanisms underlying disease development and potentially identify new targets for therapeutic intervention.
Antibody Name:
TCTEX1D2 Antibody (PACO39214)
Antibody SKU:
PACO39214
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:20-1:200
Species Reactivity:
Human
Immunogen:
Recombinant Human Tctex1 domain-containing protein 2 protein (1-142AA)
Immunohistochemistry of paraffin-embedded human small intestine tissue using PACO39214 at dilution of 1:100.
Immunohistochemistry of paraffin-embedded human ovarian cancer using PACO39214 at dilution of 1:100.
Synonyms:
Tctex1 domain-containing protein 2, TCTEX1D2
UniProt Protein Function:
TCTEX1D2: Belongs to the dynein light chain Tctex-type family.Chromosomal Location of Human Ortholog: 3q29Molecular Function: protein binding
UniProt Protein Details:
NCBI Summary:
Dyneins are a group of microtubule-activated ATPases that function as molecular motors. They are divided into two subgroups of axonemal and cytoplasmic dyneins. The cytoplasmic dyneins function in intracellular motility, including retrograde axonal transport, protein sorting, organelle movement, and spindle dynamics. Molecules of conventional cytoplasmic dynein are comprised of 2 heavy chain polypeptides and a number of intermediate and light chains. This gene encodes a subunit of the human cytoplasmic dynein-2 complex. Mutations in this gene are associated with short-rib thoracic dysplasia 17 with or without polydactyly. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2017]
