TCP1 Rabbit Polyclonal Antibody (CAB13364)
- SKU:
- CAB13364
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | TCP1 Rabbit Polyclonal Antibody |
SKU: | CAB13364 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 307-556 of human TCP1 (NP_110379.2). |
Sequence: | AVRR VLKR DLKR IAKA SGAT ILST LANL EGEE TFEA AMLG QAEE VVQE RICD DELI LIKN TKAR TSAS IILR GAND FMCD EMER SLHD ALCV VKRV LESK SVVP GGGA VEAA LSIY LENY ATSM GSRE QLAI AEFA RSLL VIPN TLAV NAAQ DSTD LVAK LRAF HNEA QVNP ERKN LKWI GLDL SNGK PRDN KQAG VFEP TIVK VKSL KFAT EAAI TILR IDDL IKLH PESK DDKH GSYE DAVH SGAL ND |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 |
Synonyms: | CCT1; CCTa; D6S230E; CCT-alpha; TCP-1-alpha; TCP1 |
Positive Sample: | MCF7,PC-3,Jurkat,U-251MG |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, centrosome, cytoskeleton, microtubule organizing center. |
Calculated MW: | 60kDa |
Observed MW: | 60kDa |
The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of this gene, encoding different isoforms, have been characterized. In addition, three pseudogenes that appear to be derived from this gene have been found.
Purification Method: | Affinity purification |
Gene ID: | 6950 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |