The TCHH Polyclonal Antibody (CAB15731) is a vital tool for researchers studying the trichohyalin (TCHH) protein, which is essential for the formation of hair follicles and the development of hair shafts. This polyclonal antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the TCHH protein, this antibody enables the detection and analysis of TCHH in a variety of cell types, making it an invaluable asset for studies in dermatology, hair biology, and related fields.
TCHH is a crucial protein in the process of hair formation and plays a key role in maintaining the structure and integrity of hair shafts. Research on TCHH is vital for understanding the mechanisms underlying hair growth, development, and disorders related to hair health. By utilizing the TCHH Polyclonal Antibody, researchers can gain insights into the function and regulation of TCHH, paving the way for advancements in the treatment of hair disorders and the development of innovative hair care products.
Product Name:
TCHH Rabbit Polyclonal Antibody
SKU:
CAB15731
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 100-300 of human TCHH (NP_009044.2).
The protein encoded by this gene forms crosslinked complexes with itself and keratin intermediate filaments to provide mechanical strength to the hair follicle inner root sheath. The encoded protein also is important for structural integrity of the filiform papillae of the tongue. Defects in this gene are a cause of uncombable hair syndrome.
Purification Method:
Affinity purification
Gene ID:
7062
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using TCHH Rabbit pAb (CAB15731) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.