The TCF7L2 Rabbit Monoclonal Antibody (CAB19548) is a high-quality antibody designed for research involving the TCF7L2 protein, a transcription factor implicated in various cellular processes, including stem cell pluripotency and glucose metabolism. This antibody, generated in rabbits, is highly specific and reactive with human samples, making it ideal for use in Western blot applications.TCF7L2 is a key player in the Wnt signaling pathway, which regulates cell proliferation, differentiation, and survival. Dysregulation of TCF7L2 has been implicated in various diseases, including cancer and diabetes.
Studying the expression and activity of TCF7L2 using this antibody can provide valuable insights into its role in these disease processes.The TCF7L2 Rabbit Monoclonal Antibody (CAB19548) is a reliable tool for researchers studying TCF7L2 function in various cell types and biological contexts. Its high specificity and sensitivity make it a valuable asset for studies in molecular biology, cancer research, and metabolic disorders. By enabling the detection and analysis of TCF7L2 protein levels, this antibody contributes to furthering our understanding of the complex pathways regulated by TCF7L2.
Product Name:
TCF4/TCF7L2 Rabbit Monoclonal Antibody
SKU:
CAB19548
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human TCF4/TCF7L2 (Q9NQB0).
This gene encodes a high mobility group (HMG) box-containing transcription factor that plays a key role in the Wnt signaling pathway. The protein has been implicated in blood glucose homeostasis. Genetic variants of this gene are associated with increased risk of type 2 diabetes. Several transcript variants encoding multiple different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
6934
Clone Number:
ARC0027
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using TCF4/TCF7L2 Rabbit mAb (CAB19548) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
