TCF4 Rabbit Polyclonal Antibody (CAB16980)
- SKU:
- CAB16980
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Developmental Biology
Frequently bought together:
Description
Product Name: | TCF4 Rabbit Polyclonal Antibody |
SKU: | CAB16980 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-210 of human TCF4 (NP_003190.1). |
Sequence: | MHHQ QRMA ALGT DKEL SDLL DFSA MFSP PVSS GKNG PTSL ASGH FTGS NVED RSSS GSWG NGGH PSPS RNYG DGTP YDHM TSRD LGSH DNLS PPFV NSRI QSKT ERGS YSSY GRES NLQG CHQQ SLLG GDMD MGNP GTLS PTKP GSQY YQYS SNNP RRRP LHSS AMEV QTKK VRKV PPGL PSSV YAPS ASTA DYNR DSPG YPSS KPAT ST |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | E2-2; FCD2; ITF2; PTHS; SEF2; CDG2T; FECD3; ITF-2; SEF-2; TCF-4; SEF2-1; SEF2-1A; SEF2-1B; SEF2-1D; bHLHb19; TCF4 |
Positive Sample: | HCT 116 |
Cellular Localization: | Nucleus. |
Calculated MW: | 71kDa |
Observed MW: | 71kDa |
This gene encodes transcription factor 4, a basic helix-loop-helix transcription factor. The encoded protein recognizes an Ephrussi-box ('E-box') binding site ('CANNTG') - a motif first identified in immunoglobulin enhancers. This gene is broadly expressed, and may play an important role in nervous system development. Defects in this gene are a cause of Pitt-Hopkins syndrome. In addition, an intronic CTG repeat normally numbering 10-37 repeat units can expand to >50 repeat units and cause Fuchs endothelial corneal dystrophy. Multiple alternatively spliced transcript variants that encode different proteins have been described.
Purification Method: | Affinity purification |
Gene ID: | 6925 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |