The TCF20 Polyclonal Antibody (PAC060404) is a valuable tool for researchers studying the TCF20 protein, a transcription factor that plays a crucial role in gene regulation. This antibody, raised in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the TCF20 protein, this antibody enables precise detection and analysis in a variety of cell types, making it ideal for research in molecular biology and genetics.TCF20 is known to be involved in the regulation of gene expression, particularly in processes such as development, differentiation, and cell growth. Its importance in these cellular functions makes it a key target for investigation in various fields, including developmental biology, cancer research, and neurobiology.
By understanding the roles and mechanisms of TCF20, researchers can gain insights into disease mechanisms and identify potential therapeutic targets for conditions such as cancer and neurological disorders.Overall, the TCF20 Polyclonal Antibody (PAC060404) is a valuable tool for researchers looking to study the function and regulation of the TCF20 protein in various biological processes. Its high specificity and reliability make it a trusted reagent for experiments aimed at unraveling the complexities of gene regulation and cellular signaling pathways.
Antibody Name:
TCF20 Antibody (PACO60404)
Antibody SKU:
PACO60404
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:200-1:500
Species Reactivity:
Human
Immunogen:
Recombinant Human Transcription factor 20 protein (539-704AA)
IHC image of PACO60404 diluted at 1:300 and staining in paraffin-embedded human brain tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
IHC image of PACO60404 diluted at 1:300 and staining in paraffin-embedded human glioma performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
Background:
Transcriptional activator that binds to the regulatory region of MMP3 and thereby controls stromelysin expression. It stimulates the activity of various transcriptional activators such as JUN, SP1, PAX6 and ETS1, suggesting a function as a coactivator.
Transcriptional activator that binds to the regulatory region of MMP3 and thereby controls stromelysin expression. It stimulates the activity of various transcriptional activators such as JUN, SP1, PAX6 and ETS1, suggesting a function as a coactivator.
NCBI Summary:
This gene encodes a transcription factor that recognizes the platelet-derived growth factor-responsive element in the matrix metalloproteinase 3 promoter. The encoded protein is thought to be a transcriptional coactivator, enhancing the activity of transcription factors such as JUN and SP1. Mutations in this gene are associated with autism spectrum disorders. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]
