The TCF15 Polyclonal Antibody (PAC054114) is a powerful tool for studying the transcription factor 15 (TCF15) protein and its role in gene regulation. This antibody, produced through rabbit immunization, is highly specific to human samples and has been validated for use in Western blot applications. By binding to TCF15, researchers can effectively study its expression and function in various cell types, making it an ideal choice for research in molecular biology and genetics.TCF15 is a transcription factor involved in the regulation of gene expression, playing a crucial role in cell differentiation, development, and metabolism.
By targeting TCF15 with this antibody, researchers can gain insights into its impact on cellular processes and potentially discover new therapeutic targets for diseases such as cancer, metabolic disorders, and developmental abnormalities. Understanding the function of TCF15 is essential for advancing our knowledge of gene regulation mechanisms and disease pathways.
Antibody Name:
TCF15 Antibody (PACO54114)
Antibody SKU:
PACO54114
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:20-1:200
Species Reactivity:
Human
Immunogen:
Recombinant Human Transcription factor 15 protein (24-199AA)
Immunohistochemistry of paraffin-embedded human cervical cancer using PACO54114 at dilution of 1:100.
Background:
May function as an early transcriptional regulator, involved in the patterning of the mesoderm and in lineage determination of cell types derived from the mesoderm.
Synonyms:
Transcription factor 15 (TCF-15) (Class A basic helix-loop-helix protein 40) (bHLHa40) (Paraxis) (Protein bHLH-EC2), TCF15, BHLHA40 BHLHEC2
UniProt Protein Function:
TCF15: May function as an early transcriptional regulator, involved in the patterning of the mesoderm and in lineage determination of cell types derived from the mesoderm.Protein type: DNA-bindingChromosomal Location of Human Ortholog: 20p13Molecular Function: transcription factor activityBiological Process: mesoderm development; regulation of transcription from RNA polymerase II promoter
UniProt Protein Details:
NCBI Summary:
The protein encoded by this gene is found in the nucleus and may be involved in the early transcriptional regulation of patterning of the mesoderm. The encoded basic helix-loop-helix protein requires dimerization with another basic helix-loop-helix protein for efficient DNA binding. [provided by RefSeq, Jul 2008]
