The TCEAL3/TCEAL5/TCEAL6 Antibody (PAC022654) is a polyclonal antibody designed for research involving the TCEAL3, TCEAL5, and TCEAL6 proteins. These proteins belong to the transcription elongation factor A-like (TCEAL) family, which plays a role in transcription regulation and cell cycle control. The antibody, raised in rabbits, is highly specific and reactive with human samples, making it suitable for various research applications.This antibody is validated for use in Western blotting, immunohistochemistry, and immunofluorescence, allowing for the detection and analysis of TCEAL3, TCEAL5, and TCEAL6 expression in different cell types and tissues.
Its versatility and reliability make it an ideal tool for studies in molecular biology, gene regulation, and cancer research.The TCEAL3/TCEAL5/TCEAL6 Antibody is a valuable resource for researchers interested in understanding the functions and mechanisms of the TCEAL family of proteins. By unraveling their roles in transcriptional regulation and cellular processes, this antibody can contribute to advancements in drug development and therapeutic strategies for diseases such as cancer and genetic disorders.
Antibody Name:
TCEAL3/TCEAL5/TCEAL6 Antibody (PACO22654)
Antibody SKU:
PACO22654
Size:
100ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:50-1:100
Species Reactivity:
Human
Immunogen:
Synthesized peptide derived from internal of human TCEAL3/5/6.
Form:
Liquid
Storage Buffer:
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using TCEAL3/5/6 antibody.
Background:
May be involved in transcriptional regulation.
Synonyms:
Transcription elongation factor A protein-like 3; TCEA-like protein 3; Transcription elongation factor S-II protein-like 3; TCEAL3; MSTP072
UniProt Protein Function:
TCEAL3: May be involved in transcriptional regulation. Belongs to the TFS-II family. TFA subfamily.Protein type: Transcription factorChromosomal Location of Human Ortholog: Xq22.2Cellular Component: nucleusBiological Process: transcription, DNA-dependent; regulation of transcription, DNA-dependent
UniProt Protein Details:
NCBI Summary:
This gene encodes a member of the transcription elongation factor A (SII)-like (TCEAL) gene family. Members of this family contain TFA domains and may function as nuclear phosphoproteins that modulate transcription in a promoter context-dependent manner. Multiple family members are located on the X chromosome. Alternative splicing results in multiple transcript variants encoding a single isoform. [provided by RefSeq, Jul 2008]
