The TBXAS1 Polyclonal Antibody (CAB13362) is a powerful tool for researchers studying the TBXAS1 protein, an enzyme involved in prostaglandin biosynthesis and inflammation. This rabbit-derived antibody is highly specific to human TBXAS1 and is validated for use in Western blot applications. It provides researchers with a reliable means of detecting and analyzing TBXAS1 protein levels in a variety of cell types, making it an essential tool for studies in immunology, inflammation, and cancer research.TBXAS1 is a key enzyme in the prostaglandin pathway, playing a crucial role in the regulation of inflammation and platelet aggregation. Dysregulation of TBXAS1 has been implicated in various inflammatory conditions, making it a promising target for therapeutic intervention.
Research on TBXAS1 could lead to the development of new treatments for inflammatory diseases, cardiovascular disorders, and cancer.By utilizing the TBXAS1 Polyclonal Antibody, researchers can gain valuable insights into the function and regulation of TBXAS1, advancing our understanding of its role in health and disease. This antibody is an essential tool for scientists working to unravel the complex mechanisms underlying inflammation and identify new therapeutic targets for a range of diseases.
Product Name:
Thromboxane synthase Rabbit Polyclonal Antibody
SKU:
CAB13362
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 355-534 of human Thromboxane synthase (NP_001052.2).
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to thromboxane A2, a potent vasoconstrictor and inducer of platelet aggregation. The enzyme plays a role in several pathophysiological processes including hemostasis, cardiovascular disease, and stroke. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
6916
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using Thromboxane synthase antibody (CAB13362) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
