Thromboxane synthase Rabbit Polyclonal Antibody (CAB13362)
- SKU:
- CAB13362
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Description
Product Name: | Thromboxane synthase Rabbit Polyclonal Antibody |
SKU: | CAB13362 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 355-534 of human Thromboxane synthase (NP_001052.2). |
Sequence: | TYLL ATNP DCQE KLLR EVDV FKEK HMAP EFCS LEEG LPYL DMVI AETL RMYP PAFR FTRE AAQD CEVL GQRI PAGA VLEM AVGA LHHD PEHW PSPE TFNP ERFT AEAR QQHR PFTY LPFG AGPR SCLG VRLG LLEV KLTL LHVL HKFR FQAC PETQ VPLQ LESK SALG PKNG VYIK IVSR |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | TS; TXS; CYP5; THAS; TXAS; CYP5A1; GHOSAL; BDPLT14; Thromboxane synthase |
Positive Sample: | THP-1,A-549,NCI-H460 |
Conjugate: | Unconjugated |
Cellular Localization: | Endoplasmic reticulum membrane, Multi-pass membrane protein. |
Calculated MW: | 61kDa |
Observed MW: | 50-56kDa |
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to thromboxane A2, a potent vasoconstrictor and inducer of platelet aggregation. The enzyme plays a role in several pathophysiological processes including hemostasis, cardiovascular disease, and stroke. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 6916 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |