The TBX6 Polyclonal Antibody (CAB16979) is a valuable tool for researchers studying the TBX6 protein, a key transcription factor involved in embryonic development and skeletal muscle formation. This antibody, produced in rabbits, exhibits high reactivity with human samples and is optimized for use in Western blot applications.TBX6 plays a crucial role in the regulation of gene expression during embryogenesis, particularly in the development of the axial skeleton and skeletal muscle. Dysregulation of TBX6 has been implicated in various congenital disorders, making it a significant target for investigation in developmental biology and genetic studies.
By specifically binding to the TBX6 protein, this antibody enables precise detection and analysis of TBX6 expression in a variety of cell types and tissues. Its versatility makes it a valuable tool for researchers exploring the molecular mechanisms underlying skeletal development, muscle differentiation, and related pathologies. Studies utilizing the TBX6 Polyclonal Antibody have the potential to advance our understanding of developmental processes and contribute to the development of new therapeutic strategies for skeletal and muscular disorders.
Product Name:
TBX6 Rabbit Polyclonal Antibody
SKU:
CAB16979
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human TBX6 (NP_004599.2).
This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. Knockout studies in mice indicate that this gene is important for specification of paraxial mesoderm structures.
Purification Method:
Affinity purification
Gene ID:
6911
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates, using TBX6 antibody (CAB16979) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
