The TBX3 Polyclonal Antibody (CAB4144) is a valuable tool for research involving TBX3, a transcription factor known for its role in embryonic development and cancer progression. This antibody is produced in rabbits and exhibits high reactivity with human samples, making it ideal for a variety of research applications.TBX3 is a critical regulator of cell proliferation, differentiation, and migration, with dysregulation implicated in various cancers and developmental disorders. The TBX3 Polyclonal Antibody binds specifically to the TBX3 protein, enabling precise detection and analysis in different cell types and tissues.
Researchers studying oncology, developmental biology, and regenerative medicine can benefit from the use of this antibody in techniques such as Western blotting, immunohistochemistry, and immunofluorescence. Understanding the function and expression of TBX3 is essential for unraveling its complex roles in normal physiology and disease pathology.By utilizing the TBX3 Polyclonal Antibody (CAB4144), scientists can gain valuable insights into the molecular mechanisms governed by TBX3, ultimately contributing to advances in cancer treatment strategies and developmental therapeutics.
Product Name:
TBX3 Rabbit Polyclonal Antibody
SKU:
CAB4144
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 310-480 of human TBX3 (NP_057653.3).
This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This protein is a transcriptional repressor and is thought to play a role in the anterior/posterior axis of the tetrapod forelimb. Mutations in this gene cause ulnar-mammary syndrome, affecting limb, apocrine gland, tooth, hair, and genital development. Alternative splicing of this gene results in three transcript variants encoding different isoforms; however, the full length nature of one variant has not been determined.
Purification Method:
Affinity purification
Gene ID:
6926
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of extracts of HepG2 cells, using TBX3 antibody (CAB4144) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
