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TBX2 Transcription Factor Activity Assay

SKU:
TFAB00169
Product Type:
ELISA Kit
ELISA Type:
Transcription Factor Assay
Analytes:
TBX2
Reactivity:
Human
Mouse
€599
Frequently bought together:

Description

system_update_altDatasheet

TBX2 Transcription Factor Activity Assay

The TBX2 Transcription Factor Activity Assay is a cutting-edge kit designed for the precise measurement of TBX2 transcription factor activity in cell lysates. With its exceptional sensitivity and specificity, this assay guarantees accurate and consistent results, making it a valuable tool for a variety of research studies.TBX2 is a crucial transcription factor that plays a pivotal role in regulating gene expression and cell growth. Dysregulation of TBX2 has been linked to various diseases, including cancer and developmental disorders.

Therefore, the TBX2 Transcription Factor Activity Assay is essential for studying the biological functions of TBX2 and identifying potential therapeutic targets for related conditions.Don't miss out on the opportunity to advance your research with the TBX2 Transcription Factor Activity Assay. Order yours today and unlock new insights into the intricate mechanisms of gene regulation and cellular processes.

Product Name:TBX2 Transcription Factor Activity Assay
Product Code:TFAB00169
Target:TBX2
Reactivity:Human, Mouse
Sample Types:Nuclear or cell lysates

The Assay Genie TBX2 transcription factor activity assay allows for the detection and qualitative analysis of endogenous levels of activated transcription factors in a variety of nuclear and cell lysates

Assay Genie ELISA kits are designed to significantly reduce experiment time and ensure sensitivity and flexibility for high-throughput screening.

Assay Time:4.5 hours
Detection Method:Colorimetric 450 nm
Size:12 x 8-Well Microstrips
Storage:4°C for 6 months
UniProt Protein Function:TBX2: Involved in the transcriptional regulation of genes required for mesoderm differentiation. Probably plays a role in limb pattern formation. Expressed primarily in adult in kidney, lung, and placenta. Weak expression in heart and ovary.
UniProt Protein Details:

Protein type:Transcription factor; DNA-binding

Chromosomal Location of Human Ortholog: 17q23.2

Cellular Component: nucleus

Molecular Function:DNA binding; protein binding; sequence-specific DNA binding

Biological Process: cardiac muscle development; cell aging; embryonic camera-type eye morphogenesis; embryonic digit morphogenesis; embryonic heart tube development; heart looping; muscle cell fate determination; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; positive regulation of cardiac muscle cell proliferation; positive regulation of cell proliferation; regulation of heart contraction

NCBI Summary:This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene product is the human homolog of mouse Tbx2, and shares strong sequence similarity with Drosophila omb protein. Expression studies indicate that this gene may have a potential role in tumorigenesis as an immortalizing agent. Transcript heterogeneity due to alternative polyadenylation has been noted for this gene. [provided by RefSeq, Jul 2008]
UniProt Code:Q13207
NCBI GenInfo Identifier:294862490
NCBI Gene ID:6909
NCBI Accession:Q13207.3
UniProt Secondary Accession:Q13207,Q16424, Q7Z647,
UniProt Related Accession:Q13207
Molecular Weight:75,066 Da
NCBI Full Name:T-box transcription factor TBX2
NCBI Synonym Full Names:T-box 2
NCBI Official Symbol:TBX2  
NCBI Protein Information:T-box transcription factor TBX2
UniProt Protein Name:T-box transcription factor TBX2
Protein Family:T-box transcription factor
UniProt Gene Name:TBX2  
UniProt Entry Name:TBX2_HUMAN
Antibodies
Anti-TBX2 Antibody (CAB10250)
TBX2 Antibody (PACO01592)
TBX2 Antibody (PACO12659)
TBX2 Antibody (PACO17909)
TBX2 Antibody (PACO54470)

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