The TBX2 Polyclonal Antibody (CAB10250) is a valuable tool for researchers studying the transcription factor TBX2, which plays a crucial role in cell growth and development. This antibody, raised in rabbits, is highly specific and reactive with human samples, making it ideal for use in various research applications such as Western blot and immunohistochemistry.TBX2 is a transcription factor that is involved in the regulation of cell proliferation, differentiation, and apoptosis. Dysregulation of TBX2 has been linked to various diseases, including cancer and developmental disorders.
By targeting TBX2 with this antibody, researchers can uncover valuable insights into the molecular mechanisms underlying these conditions.Furthermore, studying TBX2 with this antibody may lead to the development of potential therapeutic strategies for targeting TBX2-related diseases. Its versatility and specificity make it an essential tool for research in the fields of cancer biology, developmental biology, and molecular biology.
Product Name:
TBX2 Rabbit Polyclonal Antibody
SKU:
CAB10250
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 604-712 of human TBX2 (NP_005985.3).
Sequence:
GSLS RSPF LGSA RPRL RFSP YQIP VTIP PSTS LLTT GLAS EGSK AAGG NSRE PSPL PELA LRKV GAPS RGAL SPSG SAKE AANE LQSI QRLV SGLE SQRA LSPG RESP K
Tested Applications:
WBELISA
Recommended Dilution:
WB,1:1000 - 1:2000
Synonyms:
VETD; TBX2
Positive Sample:
SH-SY5Y,U-87MG,MCF7,Mouse ovary,Rat lung
Conjugate:
Unconjugated
Cellular Localization:
Nucleus.
Calculated MW:
75kDa
Observed MW:
75kDa
This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene product is the human homolog of mouse Tbx2, and shares strong sequence similarity with Drosophila omb protein. Expression studies indicate that this gene may have a potential role in tumorigenesis as an immortalizing agent. Transcript heterogeneity due to alternative polyadenylation has been noted for this gene.
Purification Method:
Affinity purification
Gene ID:
6909
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates, using TBX2 Rabbit pAb (CAB10250) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
