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TBX18/TBX15 Antibody (PACO01591)

SKU:
PACO01591
Product Type:
Antibody
Reactivity:
Human
Mouse
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
WB
IHC
IF
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
$323
Frequently bought together:

Description

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TBX18/TBX15 Antibody (PACO01591)

The TBX18/TBX15 Polyclonal Antibody (PACO01591) is a crucial tool for researchers studying the functions of the TBX18 and TBX15 proteins. These transcription factors play essential roles in regulating development and differentiation processes, particularly in the formation of various tissues and organs.This antibody, raised in rabbits, is highly specific and reactive to human samples, making it ideal for Western blot applications. By binding specifically to TBX18 and TBX15 proteins, researchers can accurately detect and analyze these molecules in various cell types and tissues.

This makes the antibody invaluable for research in developmental biology, tissue engineering, and regenerative medicine.The TBX18/TBX15 Polyclonal Antibody is essential for understanding the complex mechanisms underlying tissue development and differentiation, making it a valuable tool for researchers studying a wide range of biological processes. Its high specificity and reactivity ensure reliable and accurate results, allowing for precise analysis of TBX18 and TBX15 functions in various research contexts.

Antibody Name:TBX18/TBX15 Antibody
Antibody SKU:PACO01591
Size:50ug
Host Species:Rabbit
Tested Applications:ELISA, WB, IHC, IF
Recommended Dilutions:WB:1:500-1:2000, IHC:1:100-1:300, IF:1:200-1:1000
Species Reactivity:Human, Mouse
Immunogen:synthesized peptide derived from the Internal region of human TBX15/18.
Form:Liquid
Storage Buffer:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Synonyms:TBX18; T-box transcription factor TBX18; T-box protein 18; TBX15; TBX14; T-box transcription factor TBX15; T-box protein 15; T-box transcription factor TBX14; T-box protein 14
UniProt Protein Function:TBX18: Probable transcriptional regulator involved in developmental processes.
UniProt Protein Details:

Protein type:Transcription factor; DNA-binding

Chromosomal Location of Human Ortholog: 6q14-q15

Cellular Component: nucleus

Molecular Function:protein binding; protein heterodimerization activity; protein homodimerization activity; transcription factor activity

Biological Process: anterior/posterior axis specification; morphogenesis of embryonic epithelium; negative regulation of transcription from RNA polymerase II promoter; positive regulation of cell-cell adhesion; positive regulation of epithelial cell proliferation; sensory perception of sound; smooth muscle cell differentiation; somitogenesis; transcription, DNA-dependent

Disease: Huntington Disease

NCBI Summary:This genes codes for a member of an evolutionarily conserved family of transcription factors that plays a crucial role in embryonic development. The family is characterized by the presence of the DNA-binding T-box domain and is divided into five sub-families based on sequence conservation in this domain. The encoded protein belongs to the vertebrate specific Tbx1 sub-family. The protein acts as a transcriptional repressor by antagonizing transcriptional activators in the T-box family. The protein forms homo- or heterodimers with other transcription factors of the T-box family or other transcription factors. [provided by RefSeq, Nov 2012]
UniProt Code:O95935
NCBI GenInfo Identifier:122937456
NCBI Gene ID:9096
NCBI Accession:NP_001073977.1
UniProt Secondary Accession:O95935,Q7Z6U4, Q9UJI6, A2RU13,
UniProt Related Accession:O95935
Molecular Weight:80.8 kDa
NCBI Full Name:T-box transcription factor TBX18
NCBI Synonym Full Names:T-box 18
NCBI Official Symbol:TBX18  
NCBI Protein Information:T-box transcription factor TBX18
UniProt Protein Name:T-box transcription factor TBX18
Protein Family:T-box transcription factor
UniProt Gene Name:TBX18  
UniProt Entry Name:TBX18_HUMAN

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