TBX18 Antibody (PACO22644)
- SKU:
- PACO22644
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
TBX18 Antibody (PACO22644)
The TBX18 Polyclonal Antibody (PAC022644) is a valuable tool for researchers investigating the role of transcription factor TBX18 in various cellular processes. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By binding specifically to the TBX18 protein, researchers can detect and analyze its expression in different types of cells, making it ideal for studies in developmental biology and cardiac research.
TBX18 is a transcription factor involved in the regulation of gene expression during embryonic development, particularly in the formation of various organ systems. Its importance in cellular differentiation and tissue patterning makes it a key focus in research on congenital defects and regenerative medicine. Understanding the function of TBX18 can provide insights into potential therapeutic strategies for conditions related to organ development and regeneration.
| Antibody Name: | TBX18 Antibody (PACO22644) |
| Antibody SKU: | PACO22644 |
| Size: | 100ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:3000 |
| Species Reactivity: | Human |
| Immunogen: | Synthesized peptide derived from internal of human TBX18. |
| Form: | Liquid |
| Storage Buffer: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot analysis of extracts from Jurkat cells, using TBX18 antibody. |
| Background: | Probable transcriptional regulator involved in developmental processes. |
| Synonyms: | T-box protein 18; T-box transcription factor TBX18; TBX18; |
| UniProt Protein Function: | TBX18: Probable transcriptional regulator involved in developmental processes. |
| UniProt Protein Details: | Protein type:Transcription factor; DNA-binding Chromosomal Location of Human Ortholog: 6q14-q15 Cellular Component: nucleus Molecular Function:protein binding; protein heterodimerization activity; protein homodimerization activity; transcription factor activity Biological Process: anterior/posterior axis specification; morphogenesis of embryonic epithelium; negative regulation of transcription from RNA polymerase II promoter; positive regulation of cell-cell adhesion; positive regulation of epithelial cell proliferation; sensory perception of sound; smooth muscle cell differentiation; somitogenesis; transcription, DNA-dependent Disease: Huntington Disease |
| NCBI Summary: | This genes codes for a member of an evolutionarily conserved family of transcription factors that plays a crucial role in embryonic development. The family is characterized by the presence of the DNA-binding T-box domain and is divided into five sub-families based on sequence conservation in this domain. The encoded protein belongs to the vertebrate specific Tbx1 sub-family. The protein acts as a transcriptional repressor by antagonizing transcriptional activators in the T-box family. The protein forms homo- or heterodimers with other transcription factors of the T-box family or other transcription factors. [provided by RefSeq, Nov 2012] |
| UniProt Code: | O95935 |
| NCBI GenInfo Identifier: | 122937456 |
| NCBI Gene ID: | 9096 |
| NCBI Accession: | NP_001073977.1 |
| UniProt Secondary Accession: | O95935,Q7Z6U4, Q9UJI6, A2RU13, |
| UniProt Related Accession: | O95935 |
| Molecular Weight: | 80.8 kDa |
| NCBI Full Name: | T-box transcription factor TBX18 |
| NCBI Synonym Full Names: | T-box 18 |
| NCBI Official Symbol: | TBX18Â Â |
| NCBI Protein Information: | T-box transcription factor TBX18 |
| UniProt Protein Name: | T-box transcription factor TBX18 |
| Protein Family: | T-box transcription factor |
| UniProt Gene Name: | TBX18Â Â |
| UniProt Entry Name: | TBX18_HUMAN |
| Antibodies | ELISA Kits |
| TBX18 Antibody (PACO05688) | TBX18 Transcription Factor Activity Assay |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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TBX18 Transcription Factor Activity Assay
