The TBX10 Polyclonal Antibody (PAC017219) is a valuable tool for researchers studying TBX10, a transcription factor involved in developmental processes such as organogenesis and cell differentiation. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in techniques such as Western blotting.TBX10 is known for its important role in the regulation of gene expression during embryonic development. It is particularly involved in the formation of various tissues and organs, making it a key player in understanding developmental biology.
By targeting the TBX10 protein, researchers can investigate its functions and mechanisms in different cell types, providing insights into developmental pathways and potential therapeutic targets.With its high specificity and reactivity, the TBX10 Polyclonal Antibody is an essential tool for studies in developmental biology, stem cell research, and organogenesis. Its use can lead to a better understanding of TBX10's functions and its implications in various developmental disorders and diseases, paving the way for new insights and potential therapeutic interventions.
Antibody Name:
TBX10 Antibody (PACO17219)
Antibody SKU:
PACO17219
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:5000, IHC:1:25-1:100
Species Reactivity:
Human
Immunogen:
Fusion protein of human TBX10
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using PACO17219(TBX10 Antibody) at dilution 1/35, on the right is treated with fusion protein. (Original magnification: x200).
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO17219(TBX10 Antibody) at dilution 1/35, on the right is treated with fusion protein. (Original magnification: x200).
Background:
This gene encodes a member of the T-box family of transcription factors. These transcription factors share a DNA-binding domain called the T-box, and play a role in several developmental processes including early embryonic cell fate and organogenesis. The encoded protein is a member of the T-box 1 subfamily. Mutations in this gene are thought to be a cause of isolated cleft lip with or without cleft palate.
Synonyms:
T-box 10
UniProt Protein Function:
TBX10: Probable transcriptional regulator involved in developmental processes.
Biological Process: anatomical structure morphogenesis; regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent
NCBI Summary:
This gene encodes a member of the T-box family of transcription factors. These transcription factors share a DNA-binding domain called the T-box, and play a role in several developmental processes including early embryonic cell fate and organogenesis. The encoded protein is a member of the T-box 1 subfamily. Mutations in this gene are thought to be a cause of isolated cleft lip with or without cleft palate. [provided by RefSeq, Nov 2010]
