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TBX10 Antibody (PACO01590)

SKU:
PACO01590
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
WB
IHC
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
€269

Description

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TBX10 Antibody (PACO01590)

The TBX10 Polyclonal Antibody (PACO1590) is a valuable tool for researchers studying the TBX10 protein, which is involved in the regulation of gene expression during development. This antibody is produced in rabbits and exhibits high reactivity with human samples, making it suitable for use in various research applications such as Western blotting.TBX10 is a transcription factor that plays a critical role in the development of various tissues and organs, including the heart and lungs. Dysregulation of TBX10 expression has been linked to developmental disorders and diseases such as congenital heart defects.

By targeting TBX10 with this antibody, researchers can accurately detect and analyze the protein in different cell types, providing insights into its function and potential implications in disease mechanisms.Given the importance of TBX10 in developmental processes and disease pathology, this antibody is a valuable resource for studies in developmental biology, genetics, and cardiovascular research. Its specificity and reliability make it an essential tool for investigating the role of TBX10 in health and disease.

Antibody Name:TBX10 Antibody
Antibody SKU:PACO01590
Size:50ug
Host Species:Rabbit
Tested Applications:ELISA, WB, IHC
Recommended Dilutions:WB:1:500-1:2000, IHC:1:100-1:300
Species Reactivity:Human
Immunogen:synthesized peptide derived from the Internal region of human TBX10.
Form:Liquid
Storage Buffer:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Synonyms:TBX10; TBX7; T-box transcription factor TBX10; T-box protein 10
UniProt Protein Function:TBX10: Probable transcriptional regulator involved in developmental processes.
UniProt Protein Details:

Protein type:Transcription factor; DNA-binding

Chromosomal Location of Human Ortholog: 11q13.2

Cellular Component: nucleus

Molecular Function:DNA binding; transcription factor activity

Biological Process: anatomical structure morphogenesis; regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent

NCBI Summary:This gene encodes a member of the T-box family of transcription factors. These transcription factors share a DNA-binding domain called the T-box, and play a role in several developmental processes including early embryonic cell fate and organogenesis. The encoded protein is a member of the T-box 1 subfamily. Mutations in this gene are thought to be a cause of isolated cleft lip with or without cleft palate. [provided by RefSeq, Nov 2010]
UniProt Code:O75333
NCBI GenInfo Identifier:51338743
NCBI Gene ID:347853
NCBI Accession:O75333.2
UniProt Secondary Accession:O75333,Q14D64, Q86XS3,
UniProt Related Accession:O75333
Molecular Weight:42,341 Da
NCBI Full Name:T-box transcription factor TBX10
NCBI Synonym Full Names:T-box 10
NCBI Official Symbol:TBX10  
NCBI Official Synonym Symbols:TBX7; TBX13  
NCBI Protein Information:T-box transcription factor TBX10
UniProt Protein Name:T-box transcription factor TBX10
Protein Family:T-box transcription factor
UniProt Gene Name:TBX10  
UniProt Entry Name:TBX10_HUMAN

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