The TBPL2 Polyclonal Antibody (PAC023503) is a vital tool for researchers studying TBPL2, a key protein involved in transcription regulation. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blotting applications. By binding specifically to the TBPL2 protein, this antibody allows for precise detection and analysis in a variety of cell types, making it an optimal choice for investigations in the fields of molecular biology and gene expression studies.TBPL2, also known as TATA box-binding protein like 2, plays a crucial role in the regulation of gene transcription by interacting with key transcription factors.
Its involvement in controlling gene expression makes it a promising target for research in various areas such as developmental biology, cancer biology, and epigenetics. Understanding the function and regulation of TBPL2 is essential for unraveling the complexities of gene expression and identifying potential therapeutic targets for diseases linked to aberrant gene regulation.
Synthesized peptide derived from internal of human TBPL2.
Form:
Liquid
Storage Buffer:
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Western blot analysis of extracts from HeLa cells, using TBPL2 antibody.
Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using TBPL2 antibody.
Background:
Transcription factor required in complex with TAF3 for the differentiation of myoblasts into myocytes. The complex replaces TFIID at specific promoters at an early stage in the differentiation process By similarity. UniProtKB Q6SJ95
Synonyms:
TATA box-binding protein-like protein 2; TBP-like protein 2; TATA box-binding protein-related factor 3; TBP-related factor 3; TBPL2
UniProt Protein Function:
TBPL2: Transcription factor required in complex with TAF3 for the differentiation of myoblasts into myocytes. The complex replaces TFIID at specific promoters at an early stage in the differentiation process. Belongs to the TBP family.Protein type: DNA-binding; Transcription factorChromosomal Location of Human Ortholog: 14q22.3Cellular Component: cytoplasm; nucleus
