The TBL1X Polyclonal Antibody (CAB15102) is a valuable tool for researchers studying TBL1X, a transcriptional corepressor involved in various cellular processes such as cell differentiation and development. This antibody is produced in rabbits and is highly specific to human samples, making it ideal for Western blot applications.TBL1X is known for its role in regulating gene expression by interacting with various transcription factors and chromatin-modifying enzymes. Dysregulation of TBL1X has been implicated in diseases such as cancer, making it a promising target for therapeutic interventions.
By using the TBL1X Polyclonal Antibody, researchers can detect and analyze TBL1X levels in different cell types, providing valuable insights into its functions and potential implications for disease pathology. This antibody is a valuable tool for studies in molecular biology, oncology, and developmental biology, offering a deeper understanding of TBL1X and its involvement in cellular processes.
Product Name:
TBL1X Rabbit Polyclonal Antibody
SKU:
CAB15102
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 100-200 of human TBL1X (NP_005638.1).
The protein encoded by this gene has sequence similarity with members of the WD40 repeat-containing protein family. The WD40 group is a large family of proteins, which appear to have a regulatory function. It is believed that the WD40 repeats mediate protein-protein interactions and members of the family are involved in signal transduction, RNA processing, gene regulation, vesicular trafficking, cytoskeletal assembly and may play a role in the control of cytotypic differentiation. This encoded protein is found as a subunit in corepressor SMRT (silencing mediator for retinoid and thyroid receptors) complex along with histone deacetylase 3 protein. This gene is located adjacent to the ocular albinism gene and it is thought to be involved in the pathogenesis of the ocular albinism with late-onset sensorineural deafness phenotype. Four transcript variants encoding two different isoforms have been found for this gene. This gene is highly similar to the Y chromosome TBL1Y gene.
Purification Method:
Affinity purification
Gene ID:
6907
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using TBL1X Rabbit pAb (CAB15102) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
