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TBK1/NAK Rabbit Polyclonal Antibody (CAB2573)

SKU:
CAB2573
Product Type:
Antibody
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Immunology
€139 - €419
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:TBK1/NAK Rabbit Polyclonal Antibody
SKU:CAB2573
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 500-600 of human TBK1/NAK (NP_037386.1).
Sequence:DIHT KLLR LSSS QGTI ETSL QDID SRLS PGGS LADA WAHQ EGTH PKDR NVEK LQVL LNCM TEIY YQFK KDKA ERRL AYNE EQIH KFDK QKLY YHAT KAMT H
Tested Applications:WB IHC-P ELISA
Recommended Dilution:WB,1:500 - 1:1000 IHC-P,1:50 - 1:200
Synonyms:NAK; T2K; IIAE8; FTDALS4; TBK1/NAK
Positive Sample:HepG2,HeLa,Mouse lung,Rat thymus
Conjugate:Unconjugated
Cellular Localization:Cytoplasm.
Calculated MW:84kDa
Observed MW:84kDa

The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and nuclear translocation of the NFKB complex. The protein encoded by this gene is similar to IKB kinases and can mediate NFKB activation in response to certain growth factors. The protein is also an important kinase for antiviral innate immunity response.

Purification Method:Affinity purification
Gene ID:29110
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Product ImageWestern blot analysis of lysates from Mouse lung, using TBK1/NAK Rabbit pAb (CAB2573) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.

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