The TBCE Polyclonal Antibody (CAB16978) is specifically designed for researchers studying the TBCE protein, which plays a key role in tubulin folding and microtubule assembly. This rabbit-derived antibody is highly reactive with human samples and has been validated for use in Western blot applications. By binding to the TBCE protein, this antibody allows for the detection and analysis of TBCE in various cell types, making it a valuable tool for research in cell biology and cancer studies.TBCE, also known as tubulin-specific chaperone E, is essential for the proper folding of tubulin molecules and the formation of microtubules, which are crucial for cell division, intracellular transport, and cell morphology.
Dysregulation of TBCE has been implicated in diseases such as cancer and neurodegenerative disorders, making it an important target for further investigation. By studying the function of TBCE, researchers can gain valuable insights into cellular processes and potential therapeutic targets for related diseases.
Product Name:
TBCE Rabbit Polyclonal Antibody
SKU:
CAB16978
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 328-527 of human TBCE (NP_003184.1).
Cofactor E is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex; interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state. Two transcript variants encoding the same protein have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
6905
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Immunofluorescence analysis of mouse kidney using TBCE antibody (CAB16978) at dilution of 1:100. Blue: DAPI for nuclear staining.
