The TBCA Polyclonal Antibody (CAB13050) is a vital tool for researchers studying TBCA, a protein involved in microtubule biogenesis and stabilization. This antibody, produced in rabbits, exhibits high specificity for human samples and has been validated for use in Western blot applications. By binding to the TBCA protein, this antibody allows for precise detection and analysis in a variety of cell types, making it an essential choice for studies in cell biology, cancer research, and developmental biology.TBCA is a key player in the regulation of microtubule dynamics, which are crucial for cell division, cell motility, and organelle transport.
Dysregulation of TBCA has been implicated in various diseases, including cancer and neurodegenerative disorders. By studying the function of TBCA, researchers can gain valuable insights into the mechanisms underlying these conditions and potentially develop targeted therapies to combat them. The TBCA Polyclonal Antibody is a valuable tool for advancing our understanding of TBCA's role in health and disease.
Product Name:
TBCA Rabbit Polyclonal Antibody
SKU:
CAB13050
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-108 of human TBCA (NP_004598.1).
The product of this gene is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex; interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state. This gene encodes chaperonin cofactor A. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
6902
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using TBCA Rabbit pAb (CAB13050) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
