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TBCA Monoclonal Antibody [PAT1A5AT] (CPAB0544)

SKU:
CPAB0544
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Universal
Host Species:
Mouse
Isotype:
IgG2b
Clone:
PAT1A5AT
Applications:
WB
ELISA
$179
Frequently bought together:

Description

system_update_alt Datasheet

TBCA Monoclonal Antibody [PAT1A5AT] (CPAB0544)

The TBCA Polyclonal Antibody (CPAB0544) is a powerful tool for researchers studying the TBCA protein, which is involved in regulating microtubule dynamics and cell division. This antibody, produced in rabbits, is specifically designed for use in Western blot applications and is highly reactive with human samples.TBCA, or Tubulin Folding Cofactor A, is essential for proper folding and assembly of alpha and beta tubulin subunits, which are crucial for microtubule formation. Dysfunction in TBCA has been linked to various diseases, including cancer and neurodegenerative disorders, making it a promising target for drug development.

By using the TBCA Polyclonal Antibody, researchers can detect and analyze TBCA expression in different cell types, helping to further understand its role in cellular processes. This antibody is an invaluable tool for studies in cell biology, cancer research, and drug discovery aimed at targeting the microtubule network for therapeutic purposes.

Product Name:TBCA Antibody
Product Sku:CPAB0544
Size:5μg
Host Species:Mouse
Immunogen:Anti-human TBCA mAb is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with recombinant human TBCA amino acids 1-18 purified from Ecoli.
Clone:PAT1A5AT.
Reactivity:Other bodies
Applications:Western Blot, ELISA
Purification Method:TBCA antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
Isotype:IgG2b
Background:TBCA is a tubulin-folding protein which is involved in the early step of the tubulin folding pathway. TBCA is one of four proteins (cofactors A, D, E, and C) implicated in the pathway directing to properly folded beta-tubulin from folding intermediates. Cofactors A and D are thought to be a factor in capturing and stabilizing beta-tubulin in a quasi-native confirmation. TBCA is crucial for cell viability, if reduced it causes a decrease in the amount of soluble tubulin, alterations in microtubules and G1 cell cycle arrest. Cofactor E attaches to the cofactor D-tubulin complex, afterward, interaction with cofactor C triggers the release of tubulin polypeptides that are committed to the native state.
Synonyms:Tubulin-specific chaperone A, Tubulin-folding cofactor A, CFA, TCP1-chaperonin cofactor A, TBCA.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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