The TBC1D5 Polyclonal Antibody (CAB17059) is a valuable tool for researchers studying TBC1D5, a protein involved in cellular trafficking and membrane dynamics. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By binding to the TBC1D5 protein, this antibody enables the detection and analysis of TBC1D5 in a variety of cell types, making it ideal for research in cell biology and molecular biology.TBC1D5 is a member of the TBC (Tre-2/Bub2/Cdc16) domain-containing protein family, and is known to play a role in regulating membrane trafficking pathways.
Its involvement in processes such as endocytosis and intracellular vesicle transport makes it a promising target for studies on cellular physiology and disease mechanisms. Understanding the function of TBC1D5 can provide insights into various cellular processes and may have implications for research on conditions related to membrane dynamics and intracellular trafficking.
Product Name:
TBC1D5 Rabbit Polyclonal Antibody
SKU:
CAB17059
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 446-795 of human TBC1D5 (NP_055559.1).
Enables AP-2 adaptor complex binding activity and retromer complex binding activity. Involved in several processes, including macroautophagy; positive regulation of receptor internalization; and retrograde transport, endosome to Golgi. Located in Golgi apparatus; autophagosome; and endosome membrane. Part of retromer complex. Colocalizes with AP-2 adaptor complex and Atg1/ULK1 kinase complex.
Purification Method:
Affinity purification
Gene ID:
9779
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using TBC1D5 Rabbit pAb (CAB17059) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
