TBC1D3 Antibody (PACO21893)
- SKU:
- PACO21893
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
TBC1D3 Antibody (PACO21893)
The TBC1D3 Polyclonal Antibody (PAC021893) is a valuable tool for researchers studying TBC1D3, a protein involved in cellular processes such as cell proliferation, migration, and invasion. This antibody, produced in rabbits, exhibits high specificity and sensitivity for human samples, making it suitable for Western blot applications. By binding to the TBC1D3 protein, this antibody enables precise detection and analysis in a variety of cell types, offering great utility in studies related to cancer biology and cell signaling pathways.
TBC1D3 has been implicated in promoting tumor growth and metastasis in various cancer types, making it a promising target for cancer therapy development. Its role in regulating essential cellular functions underscores its significance in cancer progression and potentially other diseases as well. Investigating the mechanisms by which TBC1D3 influences cellular behavior is essential for advancing our understanding of disease pathology and identifying novel therapeutic strategies.
| Antibody Name: | TBC1D3 Antibody (PACO21893) |
| Antibody SKU: | PACO21893 |
| Size: | 100ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:3000 |
| Species Reactivity: | Human |
| Immunogen: | Synthesized peptide derived from internal of human TBC1D3. |
| Form: | Liquid |
| Storage Buffer: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot analysis of extracts from HeLa cells, using TBC1D3 antibody. |
| Background: | Acts as a GTPase activating protein for RAB5. Does not act on RAB4 or RAB11. Wiemann S., Genome Res. 11:422-435(2001). |
| Synonyms: | TBC1 domain family member 3; Rab GTPase-activating protein PRC17; Prostate cancer gene 17 protein; TRE17 α protein; TBC1D3 |
| UniProt Protein Function: | TBC1D3: Acts as a GTPase activating protein for RAB5. Does not act on RAB4 or RAB11 |
| UniProt Protein Details: | Protein type:Oncoprotein; GAPs; GAPs, Rab Chromosomal Location of Human Ortholog: 17q12 Cellular Component: plasma membrane |
| UniProt Code: | Q8IZP1 |
| NCBI GenInfo Identifier: | 294862542 |
| NCBI Gene ID: | |
| NCBI Accession: | Q8IZP1.5 |
| UniProt Secondary Accession: | Q8IZP1,Q9H0B9, Q9UDD4, A6NGX2, A8K007, |
| Molecular Weight: | 62,168 Da |
| NCBI Full Name: | TBC1 domain family member 3 |
| UniProt Protein Name: | TBC1 domain family member 3 |
| UniProt Synonym Protein Names: | Prostate cancer gene 17 protein; Protein TRE17-alpha; Rab GTPase-activating protein PRC17 |
| Protein Family: | TBC1 domain family |
| UniProt Gene Name: | TBC1D3Â Â |
| UniProt Entry Name: | TBC3A_HUMAN |
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