The TBC1D22A Polyclonal Antibody (PAC039498) is a valuable tool for researchers studying TBC1D22A, a member of the TBC (Tre-2/Bub2/Cdc16) domain family known to play a role in intracellular membrane trafficking and cellular signaling pathways. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications, enabling detection and analysis of TBC1D22A protein levels in various cell types.TBC1D22A is involved in various cellular processes, including vesicle trafficking and regulation of cell growth and differentiation. Its dysregulation has been linked to diseases such as cancer and neurodegenerative disorders, making it an attractive target for further research.
By studying the function and expression of TBC1D22A, researchers can gain insight into its role in disease development and potentially identify new therapeutic targets for intervention.Overall, the TBC1D22A Polyclonal Antibody is a valuable tool for investigators interested in unraveling the complexities of intracellular signaling and membrane dynamics, paving the way for future advancements in the treatment of diseases associated with TBC1D22A dysfunction.
Antibody Name:
TBC1D22A Antibody (PACO39498)
Antibody SKU:
PACO39498
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:500-1:2000
Species Reactivity:
Human, Rat
Immunogen:
Recombinant Human TBC1 domain family member 22A protein (1-280AA)
Western blot. All lanes: TBC1D22A antibody at 18µg/ml. Lane 1: Colo320 whole cell lysate. Lane 2: HepG2 whole cell lysate. Lane 3: Rat skeletal muscle tissue. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 60, 51, 37, 54 kDa. Observed band size: 60 kDa.
Background:
May act as a GTPase-activating protein for Rab family protein(s).
Synonyms:
TBC1 domain family member 22A, TBC1D22A, C22orf4
UniProt Protein Function:
TBC1D22A: May act as a GTPase-activating protein for Rab family protein(s). 3 isoforms of the human protein are produced by alternative splicing.Protein type: GAPs; GAPs, RabChromosomal Location of Human Ortholog: 22q13.3Cellular Component: endomembrane system; intracellularMolecular Function: GTPase activator activity; protein binding; protein homodimerization activity; Rab GTPase bindingBiological Process: intracellular protein transport; regulation of vesicle fusion
