The TBC1D1 Polyclonal Antibody (CAB9501) is a research tool specifically designed for studying the TBC1D1 protein, which plays a key role in cellular processes such as glucose metabolism and insulin signaling. This antibody, generated in rabbits, is highly sensitive and specific for detecting TBC1D1 in human samples, making it a valuable tool for researchers in the fields of metabolism, diabetes, and obesity.TBC1D1 is a member of the TBC1 domain family, which are proteins involved in the regulation of cellular trafficking and signaling. In particular, TBC1D1 is known to regulate the translocation of glucose transporter proteins in response to insulin, linking it to metabolic processes such as glucose uptake and storage.
Research using the TBC1D1 Polyclonal Antibody can provide insights into how TBC1D1 functions in normal and pathological conditions, offering potential targets for therapeutic interventions in metabolic disorders. By investigating the role of TBC1D1, researchers can further understand the mechanisms underlying metabolic diseases and potentially develop new strategies for their treatment.
Product Name:
TBC1D1 Rabbit Polyclonal Antibody
SKU:
CAB9501
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1069-1168 of human TBC1D1 (NP_055988.2).
TBC1D1 is the founding member of a family of proteins sharing a 180- to 200-amino acid TBC domain presumed to have a role in regulating cell growth and differentiation. These proteins share significant homology with TRE2 (USP6; MIM 604334), yeast Bub2, and CDC16 (MIM 603461) (White et al., 2000 [PubMed 10965142]).
Purification Method:
Affinity purification
Gene ID:
23216
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of HeLa cells, using TBC1D1 antibody (CAB9501) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
