The Tax1BP1 Polyclonal Antibody (CAB17039) is an essential tool for researchers studying Tax1BP1, a protein involved in a variety of cellular processes including autophagy, apoptosis, and inflammation. This antibody, raised in rabbits, is highly specific and reacts strongly with human samples, making it ideal for Western blot applications.Tax1BP1 plays a crucial role in regulating the autophagy pathway, a process that degrades and recycles damaged or unnecessary cellular components. Dysregulation of autophagy has been linked to various diseases including cancer, neurodegenerative disorders, and diabetes, making Tax1BP1 a promising target for therapeutic interventions.
By using the Tax1BP1 Polyclonal Antibody, researchers can effectively detect and analyze Tax1BP1 protein levels in different cell types, providing valuable insights into its function and potential implications in disease pathology. This antibody is a valuable tool for studies in molecular biology, cell biology, and drug development aimed at targeting autophagy for therapeutic purposes.
Product Name:
TRAF6BP/TAX1BP1 Rabbit Polyclonal Antibody
SKU:
CAB17039
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 709-789 of human TRAF6BP/TRAF6BP/TAX1BP1 (NP_006015.4).
This gene encodes a HTLV-1 tax1 binding protein. The encoded protein interacts with TNFAIP3, and inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. Degradation of this protein by caspase-3-like family proteins is associated with apoptosis induced by TNF. This protein may also have a role in the inhibition of inflammatory signaling pathways. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
8887
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Immunohistochemistry analysis of paraffin-embedded human lung cancer using TRAF6BP/TAX1BP1 Rabbit pAb (CAB17039) at dilution of 1:100 (40x lens).Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
