TRAF6BP/TAX1BP1 Rabbit Polyclonal Antibody (CAB17039)
- SKU:
- CAB17039
- Product Type:
- Antibody
- Reactivity:
- Human
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | TRAF6BP/TAX1BP1 Rabbit Polyclonal Antibody |
SKU: | CAB17039 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 709-789 of human TRAF6BP/TRAF6BP/TAX1BP1 (NP_006015.4). |
Sequence: | QHLR GHGT GFCF DSSF DVHK KCPL CELM FPPN YDQS KFEE HVES HWKV CPMC SEQF PPDY DQQV FERH VQTH FDQN VLNF D |
Tested Applications: | IHC-P ELISA |
Recommended Dilution: | IHC-P,1:50 - 1:200 |
Synonyms: | T6BP; TXBP151; CALCOCO3; TRAF6BP/TAX1BP1 |
Cellular Localization: | cytosol, extracellular exosome |
Calculated MW: | 91kDa |
Observed MW: | Refer to figures |
This gene encodes a HTLV-1 tax1 binding protein. The encoded protein interacts with TNFAIP3, and inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. Degradation of this protein by caspase-3-like family proteins is associated with apoptosis induced by TNF. This protein may also have a role in the inhibition of inflammatory signaling pathways. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 8887 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |