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TAS2R5 Antibody (PACO64539)

SKU:
PACO64539
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
IF
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
€339

Description

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TAS2R5 Antibody (PACO64539)

The TAS2R5 Antibody (PAC064539) is a polyclonal antibody designed for research involving TAS2R5, a bitter taste receptor protein involved in taste perception. The antibody is raised in rabbits and is highly reactive with human samples, validated for use in various applications such as Western blot and immunohistochemistry.TAS2R5 plays a key role in detecting bitter compounds in food and beverages, contributing to individual taste preferences and dietary choices. Research into TAS2R5 can provide insights into taste perception, food preferences, and potential links to health conditions like obesity and diabetes.

With its ability to bind specifically to TAS2R5 protein, this antibody enables reliable detection and analysis in various cell types, making it an essential tool for studies in sensory biology and nutrition research. Understanding the function and regulation of TAS2R5 can lead to advancements in food science, personalized nutrition, and therapeutic interventions targeting taste perception.

Antibody Name:TAS2R5 Antibody (PACO64539)
Antibody SKU:PACO64539
Size:50ul
Host Species:Rabbit
Tested Applications:ELISA, IF
Recommended Dilutions:IF:1:100-1:500
Species Reactivity:Human
Immunogen:Peptide sequence from Human Taste receptor type 2 member 5 protein (149-164AA)
Form:Liquid
Storage Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification Method:>95%, Antigen Affinity purified & Affinity purified
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Product ImageImmunofluorescence staining of HepG2 cells with PACO64539 at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Background:Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate α gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5.
Synonyms:Taste receptor type 2 member 5 (T2R5), TAS2R5
UniProt Protein Function:TAS2R5: Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5. Belongs to the G-protein coupled receptor T2R family.Protein type: Membrane protein, integral; Receptor, GPCR; Membrane protein, multi-pass; GPCR, T2R familyChromosomal Location of Human Ortholog: 7q31.3-q32Cellular Component: plasma membrane; integral to membraneMolecular Function: bitter taste receptor activity; taste receptor activityBiological Process: G-protein coupled receptor protein signaling pathway; sensory perception of taste; chemosensory behavior; detection of chemical stimulus involved in sensory perception of bitter taste; signal transduction
UniProt Protein Details:
NCBI Summary:This gene encodes a bitter taste receptor; bitter taste receptors are members of the G protein-coupled receptor superfamily and are specifically expressed by taste receptor cells of the tongue and palate epithelia. Each of these apparently intronless taste receptor genes encodes a 7-transmembrane receptor protein, functioning as a bitter taste receptor. This gene is clustered with another 3 candidate taste receptor genes on chromosome 7 and is genetically linked to loci that influence bitter perception. [provided by RefSeq, Jul 2008]
UniProt Code:Q9NYW4
NCBI GenInfo Identifier:9507173
NCBI Gene ID:54429
NCBI Accession:NP_061853.1
UniProt Secondary Accession:Q9NYW4
UniProt Related Accession:Q9NYW4
Molecular Weight:
NCBI Full Name:taste receptor type 2 member 5
NCBI Synonym Full Names:taste 2 receptor member 5
NCBI Official Symbol:TAS2R5  
NCBI Official Synonym Symbols:T2R5  
NCBI Protein Information:taste receptor type 2 member 5
UniProt Protein Name:Taste receptor type 2 member 5
UniProt Synonym Protein Names:
Protein Family:
UniProt Gene Name:TAS2R5  
UniProt Entry Name:TA2R5_HUMAN
Antibodies
TAS2R5 Antibody (PACO04639)
Secondary Antibody
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014)
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