The TAS2R5 Polyclonal Antibody (PACO04639) is a valuable tool for researchers studying TAS2R5, a taste receptor involved in bitter taste perception. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By targeting the TAS2R5 protein, this antibody facilitates the detection and analysis of this receptor in various cell types, making it ideal for studies in sensory biology and taste perception research.TAS2R5, a member of the TAS2R family of taste receptors, plays a crucial role in detecting bitter compounds in the diet and triggering aversive reactions to protect against potentially harmful substances.
Understanding the function of TAS2R5 is essential for unraveling the complex mechanisms of taste perception and exploring its implications for nutritional preferences and health outcomes. This antibody offers researchers a specific and reliable tool for investigating the role of TAS2R5 in taste perception and related physiological processes.
Antibody Name:
TAS2R5 Antibody
Antibody SKU:
PACO04639
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
WB:1:500-1:2000
Species Reactivity:
Human
Immunogen:
synthesized peptide derived from the Internal region of human T2R5.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
TAS2R5; Taste receptor type 2 member 5; T2R5
UniProt Protein Function:
TAS2R5: Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5. Belongs to the G-protein coupled receptor T2R family.Protein type: Membrane protein, integral; Receptor, GPCR; Membrane protein, multi-pass; GPCR, T2R familyChromosomal Location of Human Ortholog: 7q31.3-q32Cellular Component: plasma membrane; integral to membraneMolecular Function: bitter taste receptor activity; taste receptor activityBiological Process: G-protein coupled receptor protein signaling pathway; sensory perception of taste; chemosensory behavior; detection of chemical stimulus involved in sensory perception of bitter taste; signal transduction
UniProt Protein Details:
NCBI Summary:
This gene encodes a bitter taste receptor; bitter taste receptors are members of the G protein-coupled receptor superfamily and are specifically expressed by taste receptor cells of the tongue and palate epithelia. Each of these apparently intronless taste receptor genes encodes a 7-transmembrane receptor protein, functioning as a bitter taste receptor. This gene is clustered with another 3 candidate taste receptor genes on chromosome 7 and is genetically linked to loci that influence bitter perception. [provided by RefSeq, Jul 2008]
